Tatsuhiro Ishida Selected Research

DFP-10825

1/2020	An RNAi therapeutic, DFP-10825, for intraperitoneal and intrapleural malignant cancers.
12/2019	A novel intraperitoneal therapy for gastric cancer with DFP-10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model.

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Tatsuhiro Ishida Research Topics

Disease

75	Neoplasms (Cancer) 01/2024 - 04/2005
12	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 11/2010
7	Hypersensitivity (Allergy) 01/2024 - 05/2013
6	Malignant Mesothelioma 04/2020 - 01/2015
4	Inflammation (Inflammations) 12/2023 - 04/2003
4	Pancreatic Neoplasms (Pancreatic Cancer) 07/2023 - 09/2017
4	Stomach Neoplasms (Stomach Cancer) 06/2021 - 01/2018
4	Mesothelioma 04/2020 - 12/2015
3	Anaphylaxis (Anaphylactic Shock) 01/2024 - 01/2020
3	Ovarian Neoplasms (Ovarian Cancer) 07/2023 - 12/2019
3	Lewis Lung Carcinoma 01/2023 - 01/2012
3	Atherosclerosis 11/2022 - 10/2011
3	Infections 07/2020 - 05/2013
3	Neoplasm Metastasis (Metastasis) 12/2019 - 04/2005
3	Melanoma (Melanoma, Malignant) 09/2017 - 04/2008
3	Ischemia 03/2006 - 01/2002
2	Chronic Renal Insufficiency 01/2024 - 10/2016
2	Hepatitis 12/2023 - 11/2018
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2023 - 01/2022
2	Ascites 01/2022 - 06/2019
2	Neutropenia 01/2022 - 07/2020
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 05/2021 - 01/2018
2	Autoimmune Diseases (Autoimmune Disease) 05/2021 - 01/2018
2	Experimental Melanoma 01/2021 - 01/2018
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2018
2	Bacterial Infections (Bacterial Infection) 01/2018 - 10/2006
2	Colonic Neoplasms (Colon Cancer) 09/2017 - 08/2012
2	Liver Neoplasms (Liver Cancer) 01/2016 - 01/2016
2	Glossitis 01/2014 - 12/2013
2	Stomatitis 01/2014 - 12/2013
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2012 - 08/2011
2	Fibrosarcoma 08/2011 - 05/2007
1	Rhabdomyolysis 01/2024
1	Acute Kidney Injury (Acute Renal Failure) 01/2024

Drug/Important Bio-Agent (IBA)

50	Liposomes (Liposome)IBA 01/2024 - 03/2002
16	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2022 - 02/2009
15	Small Interfering RNA (siRNA)IBA 01/2022 - 08/2011
13	Therapeutic UsesIBA 01/2024 - 08/2004
13	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 07/2023 - 07/2010
11	Immunoglobulin M (IgM)IBA 01/2024 - 10/2006
7	AlbuminsIBA 12/2023 - 10/2016
7	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2007
7	Doxorubicin (Adriamycin)FDA LinkGeneric 08/2021 - 03/2002
6	Antineoplastic Agents (Antineoplastics)IBA 08/2021 - 03/2010
5	LipidsIBA 01/2024 - 07/2010
5	AntigensIBA 01/2023 - 02/2006
5	PlatinumIBA 01/2022 - 02/2009
5	Thymidylate SynthaseIBA 01/2020 - 04/2016
5	Pemetrexed (MTA)FDA Link 11/2016 - 01/2015
4	liposomal doxorubicin (Doxil)FDA Link 01/2024 - 02/2007
3	AntibodiesIBA 01/2024 - 01/2010
3	COVID-19 VaccinesIBA 01/2024 - 11/2021
3	Immunoglobulin G (IgG)IBA 01/2024 - 01/2020
3	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 10/2016
3	VaccinesIBA 01/2023 - 11/2018
3	Paclitaxel (Taxol)FDA LinkGeneric 06/2021 - 03/2021
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 09/2017
3	RNA (Ribonucleic Acid)IBA 04/2020 - 08/2011
3	human S-nitrosoalbuminIBA 01/2020 - 09/2017
3	Fluorouracil (Carac)FDA LinkGeneric 01/2017 - 11/2010
3	fasudil (AT 877)IBA 03/2006 - 01/2002
2	Serum AlbuminIBA 01/2024 - 01/2024
2	Indicators and Reagents (Reagents)IBA 01/2024 - 10/2020
2	Concanavalin AIBA 12/2023 - 11/2018
2	Peptides (Polypeptides)IBA 01/2023 - 01/2019
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2023 - 07/2020
2	Messenger RNA (mRNA)IBA 11/2022 - 11/2021
2	Blood Proteins (Serum Proteins)IBA 01/2022 - 04/2005
2	LuciferasesIBA 01/2022 - 04/2020
2	CytokinesIBA 01/2022 - 12/2013
2	Human Serum Albumin FDA LinkGeneric 08/2021 - 10/2016
2	Drug CarriersIBA 08/2021 - 08/2012
2	CelluloseIBA 06/2021 - 03/2021
2	Nucleic AcidsIBA 05/2021 - 01/2012
2	Albumin-Bound Paclitaxel FDA Link 05/2021 - 01/2021
2	DFP-10825IBA 01/2020 - 12/2019
2	Complement System Proteins (Complement)IBA 01/2019 - 01/2018
2	CholesterolIBA 01/2019 - 12/2015
2	rebamipideIBA 01/2017 - 01/2014
2	Leucovorin (Folinic Acid)FDA Link 01/2014 - 11/2010
2	amsonic acid (DAS)IBA 01/2012 - 02/2009
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 03/2009 - 04/2008
2	Matrix Metalloproteinase 14 (MT1-MMP)IBA 09/2007 - 05/2007
2	Matrix Metalloproteinases (MMPs)IBA 09/2007 - 05/2007
1	NitrogenIBA 01/2024
1	Urea (Carbamide)FDA LinkGeneric 01/2024
1	CreatinineIBA 01/2024
1	Hemoglobins (Hemoglobin)IBA 01/2024
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2024
1	AntioxidantsIBA 12/2023

Therapy/Procedure

24	Therapeutics 01/2024 - 11/2010
10	Drug Therapy (Chemotherapy) 01/2022 - 04/2008
7	Injections 01/2024 - 04/2003
5	Intravenous Administration 07/2023 - 01/2013
5	Oral Administration 10/2022 - 04/2012
4	Intravenous Injections 01/2024 - 04/2005
3	RNAi Therapeutics 01/2020 - 06/2019
2	Transplantation 01/2021 - 08/2005
2	Spinal Injections 03/2006 - 08/2004
1	Renal Dialysis (Hemodialysis) 01/2024